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Image Search Results
Journal: Bone & Joint Research
Article Title: The degenerated glenohumeral joint
doi: 10.1302/2046-3758.1310.BJR-2024-0026.R1
Figure Lengend Snippet: Immunohistochemical (IHC) scores of degeneration markers in humeral cartilage from omarthrosis (OmA), cuff tear arthropathy (CTA), and controls. Osteochondral specimens from five OmA and five CTA patients were selected that exhibited both mildly (Mankin score (MS) ≤ 7) and severely degraded (MS ≥ 8) regions. Intact cartilage regions were included from control specimens for comparison. All samples were processed for histological staining with a) Safranin O or b) to f) IHC staining with specific antibodies against b) collagen type I, c) collagen type II, d) the C1,2C neoepitope, e) collagen type X, and f) osteocalcin. *p < 0.05 vs control (Mann-Whitney U test for unpaired groups). #p < 0.05: MS < 7 vs MS > 8 (Wilcoxon test for paired groups). p-values between 0.05 and 0.1 are given in exact numbers.
Article Snippet: Immunohistochemical staining using antibodies against collagen type I (#1310-01, Southern Biotech, USA),
Techniques: Immunohistochemical staining, Control, Comparison, Staining, Immunohistochemistry, MANN-WHITNEY
Journal: Bone & Joint Research
Article Title: The degenerated glenohumeral joint
doi: 10.1302/2046-3758.1310.BJR-2024-0026.R1
Figure Lengend Snippet: Presence of matrix-associated markers in the degenerated humeral cartilage. Representative regions of intact (Mankin score (MS) 1) and severely degenerated cartilage (MS11) were selected and stained histologically with a) Safranin O and b) Picrosirius red, or immunohistochemically with specific antibodies against c) collagen type I, d) collagen type II, and e) the collagenase-generated neoepitope C1,2C. Stained sections were observed using light microscopy at 50× and 400× (inserts) magnification. Scale bars: 500 µm (MS1, 50×), 250 µm (MS11, 50×), 50 µm (400×).
Article Snippet: Immunohistochemical staining using antibodies against collagen type I (#1310-01, Southern Biotech, USA),
Techniques: Staining, Generated, Light Microscopy
Journal: Bone & Joint Research
Article Title: The degenerated glenohumeral joint
doi: 10.1302/2046-3758.1310.BJR-2024-0026.R1
Figure Lengend Snippet: Presence of chondrocyte hypertrophy-associated markers in the degenerated humeral cartilage. Representative regions of intact (MS1) and severely degenerated cartilage (MS11) were selected and stained histologically with a) Safranin O and b) Picrosirius red, or immunohistochemically with specific antibodies against c) collagen type X or d) osteocalcin. Stained sections were observed using light microscopy at 50× and 400× (inserts) magnification. Scale bars: 500 µm (MS1, 50×), 250 µm (MS11, 50×), 50 µm (400×).
Article Snippet: Immunohistochemical staining using antibodies against collagen type I (#1310-01, Southern Biotech, USA),
Techniques: Staining, Light Microscopy